Success Story
March 26, 2025

Hyperscanning Multi-physiology Acquisition Setup for UZH Neuroeconomics Lab

The Zurich Center for Neuroeconomics at the University of Zurich, a leading researcher in neuroeconomics, decision making, and self-control, recently expanded their research capabilities through the acquisition of ten synchronized BIOPAC MP200 systems from NEUROSPEC. This advanced multi-subject biosignal acquisition setup enables simultaneous physiological monitoring of multiple participants during complex social decision-making experiments.

Hyperscanning Multi-physiology Acquisition Setup for UZH Neuroeconomics Lab

Research Application and Experimental Design

The UZH Neuroeconomics lab conducts cutting-edge research examining the physiological correlates of economic decision-making processes, particularly focusing on social interactions and strategic choice behaviors. Their experimental protocols require simultaneous ECG (heart rate variability) and respiration monitoring from multiple participants as they engage in interactive economic games and decision-making tasks.

The research paradigm involves participants making strategic decisions while their autonomic nervous system responses are continuously monitored. ECG-derived heart rate variability (HRV) parameters provide insights into cognitive load, emotional regulation, and stress responses during high-stakes decision scenarios. Concurrent respiration monitoring reveals additional autonomic indicators of decision-making processes and social interaction dynamics.

The synchronized data acquisition is critical for analyzing inter-subject physiological synchrony during collaborative or competitive decision-making tasks, enabling researchers to identify physiological markers of social coordination and strategic thinking processes.

MP200 Multi-Subject Acquisition System: Technical Specifications and Capabilities

The BIOPAC MP200 represents the gold standard for multi-channel physiological data acquisition in research environments. Key technical specifications for the neuroeconomics application include:

Acquisition Parameters:

  • 16-bit A/D resolution with 0.0015% accuracy across full scale
  • Sampling rates up to 10,000 Hz per channel with anti-aliasing filters
  • Common mode rejection ratio: >110dB at 50/60Hz
  • Input impedance: >100MΩ for optimal signal quality with high-impedance electrodes
  • Gain settings: x50 to x5000 with 0.5% accuracy

ECG and HRV Measurement Capabilities:

  • Bandwidth: 0.05-1000Hz for full spectrum ECG acquisition
  • R-wave detection algorithms with <1ms temporal resolution
  • Real-time HRV parameter calculation (RMSSD, pNN50, frequency domain analysis)
  • Artifact detection and rejection algorithms for movement-robust recordings

Synchronization Architecture and Technical Implementation

NEUROSPEC designed a comprehensive synchronization solution to meet the demanding requirements of multi-subject neuroeconomics research:

STP100D Synchronization Modules: Ten STP100D stimulus/trigger interface modules provide microsecond-precise synchronization across all MP200 units. Each module features:

  • TTL trigger input/output with <1μs latency
  • Galvanic isolation to prevent ground loop interference
  • Manual and remote trigger capabilities
  • LED status indicators for real-time synchronization verification

Master Trigger System: A centralized trigger button initiates simultaneous recording across all ten MP200 systems, ensuring temporal alignment of physiological responses to experimental events. The trigger system provides:

  • Single-point recording initiation for all subjects
  • Synchronized event marking for stimulus presentation timing
  • Time-locked data acquisition for inter-subject correlation analysis
  • Automated timestamp generation for post-processing alignment

BioNomadix Wireless Integration: The BN-RSPEC wireless modules eliminate the technical challenges associated with multi-subject wired recordings:

  • Individual ground references for each subject prevent ground loop artifacts
  • 2.4GHz digital transmission with 99.7% data reliability
  • Range up to 50 meters for flexible experimental setups
  • Real-time signal quality monitoring and automatic gain adjustment

Why MP200 Systems for Multi-Subject Neuroeconomics Research

NEUROSPEC recommended the MP200 platform specifically for the UZH Neuroeconomics lab's multi-subject requirements based on several critical technical and methodological factors:

Temporal Synchronization Precision: The MP200's hardware-based synchronization capabilities ensure sub-millisecond alignment across all acquisition systems, essential for analyzing physiological responses to discrete decision-making events and inter-subject synchrony patterns.

Signal Quality and Artifact Rejection: The system's high common mode rejection ratio and advanced filtering algorithms maintain signal integrity despite the electrical noise inherent in multi-subject laboratory environments with computers, displays, and other electronic equipment.

Wireless Capability with Ground Isolation: The BioNomadix integration eliminates ground loop issues that commonly plague multi-subject wired setups, while allowing participants to move naturally and interact physically during experimental tasks.

Scalable Multi-Channel Architecture: The MP200 platform's modular design enables expansion from single-subject to multi-subject configurations without compromising per-channel specifications or requiring complete system redesign.

Real-Time Processing Capabilities: Hardware-based HRV calculation and respiratory parameter extraction provide immediate feedback on data quality and physiological responses, crucial for adaptive experimental protocols.

Research Outcomes and Methodological Advantages

The implementation of synchronized MP200 systems has enabled the UZH Neuroeconomics lab to conduct unprecedented multi-subject physiological studies of social decision-making processes. The system's capabilities support several methodological advances:

Inter-Subject Physiological Synchrony Analysis: Synchronized data acquisition enables correlation analysis of HRV patterns between interacting participants, revealing physiological markers of social coordination and strategic alignment.

Event-Related Autonomic Response Profiling: Precise temporal synchronization with experimental stimuli allows detailed analysis of autonomic responses to specific decision events, providing insights into the temporal dynamics of economic decision-making processes.

Group-Level Physiological Dynamics: The multi-subject setup enables investigation of group-level physiological phenomena during collaborative tasks, including synchronization of respiratory patterns and heart rate dynamics during collective decision-making.

Artifact-Free Social Interaction Studies: The wireless BioNomadix integration allows natural subject interaction without movement restrictions, enabling ecologically valid social decision-making paradigms while maintaining high-quality physiological recordings.

About the Collaboration

NEUROSPEC's technical consultation and system integration for the UZH Neuroeconomics Lab demonstrates our expertise in designing sophisticated multi-subject physiological monitoring solutions for demanding research applications. The successful deployment of synchronized MP200 systems validates our technical approach to complex biosignal acquisition challenges in social neuroscience research.

This collaboration exemplifies how advanced technical planning and specialized equipment selection can enable breakthrough research methodologies in neuroeconomics and decision neuroscience, establishing NEUROSPEC as the preferred partner for cutting-edge multi-subject physiological monitoring applications.

Marcus Mosimann
CMO
|
Switzerland
Marcus Mosimann is the creative force behind NEUROSPEC’s marketing and branding, shaping the company’s visual identity and communication strategy. With a deep passion for design and an exceptional attention to detail, he ensures every aspect of NEUROSPEC’s messaging is both compelling and visually striking.
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