D440

D440

Digitimer
Low-noise 2-/4-Channel EMG Amplifier

The Digitimer D440 Isolated Amplifier is a high-performance, low-noise solution specifically developed for human EMG recording and nerve excitability studies. Compact and standalone in design, the D440 combines exceptional signal quality with flexible connectivity and software integration, making it an ideal tool for advanced electrophysiological research.

Engineered to deliver reliable, low-noise signal amplification, the D440 features a wide amplification range (x100 to x20,000), AC and DC recording modes, and selectable filters to optimize recordings across a wide range of experimental needs. Each input channel is independently controlled, allowing researchers to precisely tailor their setup, whether working with two or four recording sites.

Designed to integrate seamlessly into modern research workflows, the D440 supports USB-based software control via its included Virtual Front Panel and COM interface, making it compatible with custom software applications and third-party platforms like QtracW. This makes it especially well-suited for users performing threshold tracking and nerve excitability measurements, particularly in combination with the Digitimer DS5 Constant Current Stimulator.

Standard electrode connectors (1.5mm DIN and 5-pin DIN) ensure compatibility with existing lab setups, while analog BNC outputs provide straightforward connectivity to any data acquisition (DAQ) system. Each unit is supplied with all necessary interface and electrode cables, enabling fast and efficient setup in any research environment.

The D440 also includes a manual and externally triggerable deblock function, helping to minimize stimulation artifacts such as those generated during magnetic stimulation. Channels not in use can be electronically grounded, reducing system noise and ensuring clean, accurate data.

Application Fields

  • Nerve excitability studies using QtracW and DS5
  • Threshold tracking protocols
  • EMG recordings in human research settings
  • Electrophysiology labs seeking flexible, low-noise amplification
  • Research environments requiring software-controlled analog amplifiers
  • Applications involving AC or DC bio-signal acquisition

Key Features

  • Available in 2-channel (D440-2) and 4-channel (D440-4) configurations
  • AC and DC differential recording modes
  • Independent gain settings for each channel: x100 to x20,000
  • Selectable low-cut filters: DC, 0.159 Hz, 1 Hz, 3 Hz, 5 Hz, 10 Hz, 30 Hz, 50 Hz
  • Selectable high-cut filters: 1 kHz, 3 kHz, 5 kHz, 10 kHz (Bessel style)
  • Electrode grounding switch per channel to reduce cross-talk
  • Manual and TTL-triggered Deblock control to reduce artifacts
  • USB connection for software control via included Virtual Front Panel
  • COM interface for integration with third-party software
  • Standard electrode connectors: 1.5mm DIN 42802 and 5-pin DIN
  • Supplied with all required cables (signal output, electrode input, USB)
  • Standalone operation - retains settings without PC connection
  • Mains operation: 115–230V (switch selectable), 50–60 Hz
  • Rear panel BNC output for Channel 1 and 9-way D connector for all outputs

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Read more
Number of channels:D440-2: 2
D440-4: 4
Gain:x100 (10mV/V) - x20,000 (50µV/V)
Input impedance:1GOhm (each channel)
Low-cut filter:Selectable between 0 (DC), 0.159 Hz, 1Hz, 3Hz, 5Hz, 10Hz, 30 Hz, and 50Hz for -3dB and are first order.
High-cut filter:Selectable between 1000Hz, 3000Hz, 5000Hz, and 10kHz for -3dB and are second order, low phase shift Bessel style filters.
Common Mode Rejection:-132dB @ 10Hz, -130dB @ 50Hz, -126dB @1kHz
On/off control of individual channels:The electronic inputs of individual channels can be grounded reducing cross-talk noise when recording from fewer channels. This also disconnects the subject from the electronics.
Common ‘Driven Right Leg’ system:With adjustable gain for lower noise.
Outputs:±5V range. The rear panel has a BNC socket for monitoring the output of channel 1 (this signal is mirrored on a 9-way 'D' connector on the rear panel along with the output signals of channels 2, 3 and 4). A signal output cable terminated with an appropriate number of BNC connections is supplied with each amplifier.

Important Note: This product is for research applications only. Not a medical device as defined in Regulation (EU) 2017/745 (EU MDR), Swiss Medical Devices Ordinance (MedDO, SR 812.213), or FDA 21 CFR Part 860. Not designed or intended to be used for diagnosis, treatment of disease or any other medical purposes.

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