DS4

DS4

Digitimer
Bi-Phasic Stimulus Isolator

The DS4 Bi-Phasic Current Stimulator is designed for life scientists who require a high-performance stimulus isolator capable of delivering a bi-phasic isolated constant current stimulus based on an external command voltage signal. The DS4 is specifically built for animal and in vitro electrophysiological applications where low noise and precision are paramount. This standalone stimulator offers advanced features not typically found in traditional stimulator designs, providing flexible waveform generation with enhanced signal integrity.

Unlike other systems such as the NeuroLog Series NL512 Biphasic Buffer and NL800A Stimulus Isolators, the DS4 offers a compact, versatile solution without the need for a computer-based system, giving researchers more freedom in their experiments. It excels at low-noise output, making it ideal for applications where signal purity is critical.

Precision and Versatility

The DS4 operates as a voltage-to-current amplifier, converting a biphasic voltage waveform into a proportional constant current stimulus. This allows for monophasic and biphasic stimuli that can vary in shape from rectangular pulses to sine waves or even completely arbitrary waveforms. It features two input sockets:

  • Main INPUT socket: for applying the command voltage signal
  • Optional GATE input: enables control over the stimulation via TTL logic, effectively acting as a "soft on/off switch."

Low Noise, High Accuracy

The low-noise output stage is powered by a DC supply for the control circuitry and two battery banks for the optically isolated stimulus voltage. This isolation helps minimize interference and ensures high-fidelity stimulation, even in sensitive applications. Additionally, the frequency response of the DS4 extends up to 50kHz (with -3dB roll-off), supporting rapid waveform changes and ensuring reliable operation at frequencies up to 5kHz.

Inactivity Sensor for Battery Efficiency

The DS4 features an innovative inactivity sensor that monitors the command signal voltage. If the signal falls below 0.15% of its full scale (in either positive or negative directions), the output is automatically disabled to conserve battery power and prevent unwanted stimulation. This feature helps reduce battery drain and eliminate leak currents during infrequent stimulations while maintaining minimal waveform distortion for repetitive waveforms. The inactivity sensor timeout can be adjusted between 200ms, 500ms, 1s, or 2s using accessible jumpers in the battery compartment.

Reliable and Efficient Design

  • Power Supply: The DS4 uses an external DC power supply to power the input control circuitry, while its battery-operated output stage ensures portability and energy efficiency.
  • Compact and Expandable: The DS4 is compatible with a 19" rack mount frame (D121-11), supporting up to two DS4 devices for easy integration into larger experimental setups.
  • Wide Compatibility: The DS4 works seamlessly with a variety of external voltage sources, offering compatibility with common experimental control systems.

Read more
OutputBi-phasic constant current proportional to the input voltage
Output Ranges±10µA; ±100µA; ±1mA; ±10mA for a full-scale input
Output Duration>2µs
Compliance±48V from 8x GP23A batteries
Linearity±3% of full scale output for each output range
Output Impedance>900MOhms
Output Rise Time>5us (1kOhm load), >40us (1MOhm load)
Input IN±1; ±2.5; ±5; ±10 V full scale (selected by an internal jumper) with a limit of ±12V max without damage (Input Impedance: 1MOhm)
Input GATETTL; Gate OFF if Low; Gate ON if High or open circuit with a limit of ±15V max. (Input Impedance: 10kOhm)
Dimensions (W x H x D)190 x 110 x 80
Weight500g (approx.)

Important Note: This product is for research applications only. Not a medical device as defined in Regulation (EU) 2017/745 (EU MDR), Swiss Medical Devices Ordinance (MedDO, SR 812.213), or FDA 21 CFR Part 860. Not designed or intended to be used for diagnosis, treatment of disease or any other medical purposes.

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